BASIC MEDICAL SCIENCE: PATHOLOGY AND IMMUNOLOGY
he Pathology Department conducts research into anatomical and clinical correlations in human pathology, and in the fields of cell biology, general immunology and immunopathology.
Concerning cell biology, several teams study:
- growth factors and the oncogenes involved in the differentiation and functioning of the lymphohematopoietic system;
- the functional role of certain parts of the cytoskeletal apparatus, in particular actin and intermediary filaments, and how they change in the course of the arterial pathology of scar-tissue formation and the development of epithelial tumours and conjunctive tissue;
- the structure and function of the cell membrane.
- the functional specificities in vivo of the T-lymphocyte subpopulations in a variety of experimental diseases;
- the conditions of synthesis and the role of the interleukins secreted by lymphoid system cells in different experimental and pathological conditions.
- the cell interactions leading to the development of spontaneous or provoked auto-immune diseases;
- the role of specific interactions between immunoglobulin molecules in provoking vascular lesions caused by immune complexes;
- the role of the immune response in the pathological symptoms of infectious diseases.
RESEARCH GROUPS |
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Chief of the department: Prof. Walter Reith |
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