S. HARBARTH  Head of group CV  Members of the group

  Links about the group

Prof. Stephan HARBARTH
HUG
Direction Médicale
Rue Gabrielle-Perret-Gentil 4
1211 Genève 14
Suisse

Stephan.Harbarth@hcuge.ch

Tel.: 022 372 33 57



Comments



Pages updated the 17.11.2015
Reseach's subject | Group's publications | Research's domains

MRSA

Since the last third of 1999, Geneva University Hospitals (HUG) have experienced resurgence of the previously controlled MRSA epidemic. In 2000, the incidence of MRSA (infected and colonized patients) has markedly increased over its peak value before control measures were implemented in 1994. The grave consequences of the epidemic, both for hospitalized patients and the institution have been extensively described. Briefly, hyperendemicity has led to a 4-fold increase in rate of MRSA bloodstream infection in 2000-2001, compared with annual rates during 1996-1998.
New cases are essentially the result of cross-transmission. These cases could have been prevented with adequate hand hygiene and contact isolation. A major obstacle to prompt isolation is the large unrecognized MRSA reservoir circulating among healthcare facilities. Ample evidence suggests that the early detection of occult MRSA carriers admitted in the hospital is a crucial step in controlling nosocomial transmission infection.
It is probable that by defining a specific risk-profile for admission-carriage of MRSA, a significantly lower percentage of admissions could be screened to detect the potential reservoir admitted at HUG. A targeted screening of high-risk patients (combined with a rapid detection technique) would facilitate planning for timely isolation while minimizing disruption in patient care. We therefore conduct different studies to evaluate the high-risk profile for on-admission carriage of MRSA and improve patient safety by early isolation.




Group's publications

Quasiexperimental study of the effects of antibiotic use, gastric acid-suppressive agents, and infection control practices on the incidence of Clostridium difficile-associated diarrhea in hospitalized patients.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
2009 vol. 53(5) pp. 2082-2088
ALDEYAB MA, HARBARTH S, VERNAZ N, KEARNEY MP, SCOTT MG, FUNSTON C, SAVAGE K, KELLY D, ALDIAB MA, MCELNAY JC

Adequacy of antimicrobial treatment and outcome of Staphylococcus aureus bacteremia in 9 Western European countries.
CLINICAL INFECTIOUS DISEASES
2009 vol. 49(7) pp. 997-1005
AMMERLAAN HS AND AL.

Gram-Negative Bacteremia upon Hospital Admission: When Should Pseudomonas aeruginosa Be Suspected?
CLINICAL INFECTIOUS DISEASES
2009 vol. 48(5) pp. 580-586
SCHECHNER V. AND AL.

Navigating the Web in Search of Resources on Antimicrobial Stewardship in Health Care Institutions
CLINICAL INFECTIOUS DISEASES
2009 vol. 48(5) pp. 626-632
PAGANI L, GYSSENS IC, HUTTNER B, NATHWANI D, HARBARTH S

Community-associated methicillin-resistant Staphylococcus aureus: risk factors for infection, and long-term follow-up.
CLINICAL MICROBIOLOGY AND INFECTION
2009 vol. 15(6) pp. 552-559
LONGTIN Y, SUDRE P, FRANCOIS P, SCHRENZEL J, ARAMBURU C, PASTOR R, GERVAIX A, RENZI G, PITTET D, HARBARTH S

Management of methicillin-resistant Staphylococcus aureus infections.
CLINICAL MICROBIOLOGY AND INFECTION
2009 vol. 15(2) pp. 125-136
GARAU J, BOUZA E, CHASTRE J, GUDIOL F, HARBARTH S

When once is not enough--further evidence of procalcitonin-guided antibiotic stewardship.
CRITICAL CARE
2009 vol. 13(4) pp. 165-165
HARBARTH S, ALBRICH WC, MULLER B

Methicillin-resistant Staphylococcus aureus decolonization: "yes, we can," but will it help?
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2009 vol. 30(7) pp. 633-635
KLUYTMANS J, HARBARTH S

Impact of a Short Period of Pre-Enrichment on Detection and Bacterial Loads of Methicillin-Resistant Staphylococcus aureus from Screening Specimens
JOURNAL OF CLINICAL MICROBIOLOGY
2009 vol. 47(10) pp. 3326-3328
VAN HEIRSTRAETEN L, CORTIÑAS ABRAHANTES J, LAMMENS C, LEE A, HARBARTH S, MOLENBERGHS G, AERTS M, GOOSSENS H, MALHOTRA-KUMAR S

Poor utility of MRSA screening to predict staphylococcal species in orthopaedic implant infections
JOURNAL OF HOSPITAL INFECTION
2009 vol. 73(1) pp. 89-91
UCKAY I, TETERYCZ D, FERRY T, HARBARTH S, LUBBEKE A, EMONET STEPHANE, CHILCOTT M, HOFFMEYER P, BERNARD L

"Antibiotics are not automatic anymore"--the French national campaign to cut antibiotic overuse.
PLOS MEDICINE
2009 vol. 6(6) pp. 1000080-1000080
HUTTNER B, HARBARTH S

Surveillance of extended-spectrum-beta-lactamase-producing Enterobacteriaceae in a Swiss Tertiary Care Hospital.
SWISS MEDICAL WEEKLY
2009 vol. 139(51-52) pp. 747-751
FANKHAUSER C, ZINGG W, FRANCOIS P, DHARAN S, SCHRENZEL J, PITTET D, HARBARTH S

Activity and impact on antibiotic use and costs of a dedicated infectious diseases consultant on a septic orthopaedic unit.
THE JOURNAL OF INFECTION
2009 vol. 58(3) pp. 205-212
UCKAY I, VERNAZ-HEGI N, HARBARTH S, STERN R, LEGOUT L, VAUTHEY L, FERRY T, LUBBEKE A, ASSAL M, LEW D, HOFFMEYER P, BERNARD L

Re: help or hindrance? Is current infection control advice applicable in low- and middle-income countries? A review of the literature.
AMERICAN JOURNAL OF INFECTION CONTROL
2008 vol. 36(7) pp. 499-501
STORR J, PITTET D

Use of procalcitonin to shorten antibiotic treatment duration in septic patients: a randomized trial.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2008 vol. 177(5) pp. 498-505
NOBRE V, HARBARTH S, GRAF JEAN-DANIEL, ROHNER P, PUGIN J

Novel microarray design strategy to study complex bacterial communities.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2008 vol. 74(6) pp. 1876-1885
HUYGHE ANTOINE, FRANCOIS P, CHARBONNIER YVAN, BENTO M, BONETTI EJ, PASTER BJ, BOLIVAR I, BARATTI-MAYER D, PITTET D, SCHRENZEL J

Ventilator-associated pneumonia as a quality indicator for patient safety?
CLINICAL INFECTIOUS DISEASES
2008 vol. 46(4) pp. 557-563
UCKAY ILKER, AHMED QA, SAX H, PITTET D

Healthcare-associated infections: think globally, act locally.
CLINICAL MICROBIOLOGY AND INFECTION
2008 vol. 14(10) pp. 895-907
MARCEL JP AND AL.

Healthcare-associated infections in neonates.
CURRENT OPINION IN INFECTIOUS DISEASES
2008 vol. 21(3) pp. 228-234
ZINGG W, POSFAY-BARBE KLARA, PITTET D

Methicillin-resistant Staphylococcus aureus control in the 21st century: beyond the acute care hospital.
CURRENT OPINION IN INFECTIOUS DISEASES
2008 vol. 21(4) pp. 372-379
NAVARRO M, HUTTNER B, HARBARTH S

Methicillin-resistant Staphylococcus aureus, Geneva, Switzerland, 1993-2005.
EMERGING INFECTIOUS DISEASES (PRINT)
2008 vol. 14(2) pp. 304-307
FRANCOIS P, HARBARTH S, HUYGHE ANTOINE, RENZI G, BENTO M, GERVAIX A, PITTET D, SCHRENZEL J

Commentary: hand hygiene: it's all about when and how.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2008 vol. 29(10) pp. 957-959
PITTET D

Trial of alcohol-based hand gel in critical care units.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2008 vol. 29(6) pp. 577-579
MERMEL LA, BOYCE JM, VOSS A, ALLEGRANZI B, PITTET D

Effect of screening for methicillin-resistant Staphylococcus aureus carriage by polymerase chain reaction on the duration of unnecessary preemptive contact isolation.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2008 vol. 29(11) pp. 1077-1079
UCKAY ILKER, SAX H, ITEN A, CAMUS V, RENZI G, SCHRENZEL J, PERRIER A, PITTET D

Risk factors for methicillin-resistant Staphylococcus aureus surgical site infection.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2008 vol. 29(9) pp. 890-893
HARBARTH S, HUTTNER B, GERVAZ P, FANKHAUSER C, CHRAITI MARIE-NOELLE, SCHRENZEL J, LICKER M, PITTET D

Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients.
JAMA
2008 vol. 299(10) pp. 1149-1157
HARBARTH S, FANKHAUSER C, SCHRENZEL J, CHRISTENSON JAN, GERVAZ P, BANDIERA-CLERC C, RENZI G, VERNAZ N, SAX H, PITTET D

Antibiotic prophylaxis before invasive dental procedures in patients with arthroplasties of the hip and knee.
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
2008 vol. 90(7) pp. 833-838
UCKAY ILKER, PITTET D, BERNARD L, LEW D, PERRIER A, PETER R

Infection control as a major World Health Organization priority for developing countries.
JOURNAL OF HOSPITAL INFECTION
2008 vol. ;68(4) pp. 285-292
PITTET D, ALLEGRANZI B, STORR J, BAGHERI NEJAD S, DZIEKAN G, LEOTSAKOS A, DONALDSON L

Multi-resistant infections in repatriated patients after natural disasters: lessons learned from the 2004 tsunami for hospital infection control.
JOURNAL OF HOSPITAL INFECTION
2008 vol. 68(1) pp. 1-8
UCKAY ILKER, SAX H, HARBARTH S, BERNARD L, PITTET D

Rapid and high-throughput genotyping of Staphylococcus epidermidis isolates by automated multilocus variable-number of tandem repeats: a tool for real-time epidemiology.
JOURNAL OF MICROBIOLOGICAL METHODS
2008 vol. 72(3) pp. 296-305
FRANCOIS P, HOCHMANN A, HUYGHE ANTOINE, BONETTI EJ, RENZI G, HARBARTH S, KLINGENBERG C, PITTET D, SCHRENZEL J

A predictive model for identifying surgical patients at risk of methicillin-resistant Staphylococcus aureus carriage on admission.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
2008 vol. 207(5) pp. 683-689
HARBARTH S, SAX H, UCKAY I, FANKHAUSER C, AGOSTINHO A, CHRISTENSON JT, RENZI G, SCHRENZEL J, PITTET D

Rapid identification of hospitalized patients at high risk for MRSA carriage.
JOURNAL OF THE AMERICAN MEDICAL INFORMATICS ASSOCIATION : JAMIA
2008 vol. 15(4) pp. 506-512
EVANS RS AND AL.

Community-acquired methicillin-resistant Staphylococcus aureus infections in two scuba divers returning from the Philippines.
JOURNAL OF TRAVEL MEDICINE : OFFICIAL PUBLICATION OF THE INTERNATIONAL SOCIETY OF TRAVEL MEDICINE AND THE ASIA PACIFIC TRAVEL HEALTH ASSOCIATION
2008 vol. 15(5) pp. 378-381
BOCHET M, FRANCOIS P, LONGTIN Y, GAIDE O, RENZI G, HARBARTH S

Preventing infections acquired during health-care delivery.
LANCET
2008 vol. 372(9651) pp. 1719-1720
PITTET D, ALLEGRANZI B

Alcohol-based rubs for hand antisepsis.
LANCET INFECTIOUS DISEASES
2008 vol. 8(10) pp. 585-586
PITTET D, DHARAN S

Infection control in paediatrics.
LANCET INFECTIOUS DISEASES
2008 vol. ;8(1) pp. 19-31
POSFAY-BARBE, ZERR DM, PITTET D

Cefuroxime prophylaxis is effective in noninstrumented spine surgery: a double-blind, placebo-controlled study.
SPINE
2008 vol. 33(18) pp. 1919-1924
PETIGNAT C AND AL.

Comment on: Control of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae using a computer-assisted management program to restrict third-generation cephalosporin use.
THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2008 vol. 62(5) pp. 1165-1165
HUTTNER B, PITTET D, HARBARTH S

Interventions to control MRSA: high time for time-series analysis?
THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2008 vol. 62(3) pp. 431-433
HARBARTH S, SAMORE MH

Temporal effects of antibiotic use and hand rub consumption on the incidence of MRSA and Clostridium difficile.
THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2008 vol. 62(3) pp. 601-607
VERNAZ N, SAX H, PITTET D, BONNABRY P, SCHRENZEL J, HARBARTH S

Procalcitonin guided antibiotic therapy and hospitalization in patients with lower respiratory tract infections: a prospective, multicenter, randomized controlled trial
BMC HEALTH SERVICES RESEARCH
2007 vol. 7 pp. 102-
SCHUETZ P, CHRIST-CRAIN M, WOLBERS M, SCHILD U, THOMANN R, FALCONNIER C, WIDMER I, NEIDERT S, BLUM CA, SCHÖNENBERGER R, HENZEN C, BREGENZER T, HOESS C, KRAUSE M, BUCHER HC, ZIMMERLI W, MÜLLER B, PROHOSP STUDY GROUP

Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia
BMC INFECTIOUS DISEASES
2007 vol. 7 pp. 0-0
MULLER, B, HARBARTH STEPHAN, STOLZ, D, BINGISSER, R, MUELLER, C, LEUPPI, J, NUSBAUMER, C, TAMM, M, CHRIST-CRAIN, M

Diagnostic and prognostic accuracy of clinical and laboratory parameters in community-acquired pneumonia
BMC INFECTIOUS DISEASES
2007 vol. 2 pp. 7-10
MULLER B, HARBARTH S, STOLZ D, BINGISSER R, MUELLER C, LEUPPI J, NUSBAUMER C, TAMM M, CHRIST-CRAIN M

Does antibiotic selection impact patient outcome?
CLINICAL INFECTIOUS DISEASES
2007 vol. 44 pp. 87-93
HARBARTH S, NOBRE V, PITTET D

Paediatricians' perception of antibiotic use in children in two large Swiss cities
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
2007 vol. 30 pp. 281-283
GERVAIX A, EGGER M, LACROIX L, HARBARTH S

Prevention of primary bacteraemia
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
2007 vol. 30 pp. 80-87
JUAN-TORRES, A, HARBARTH, S

Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus
JOURNAL OF CLINICAL MICROBIOLOGY
2007 vol. 45 pp. 2011-2013
FRANCOIS P, BENTO M, RENZI G, HARBARTH S, PITTET D, SCHRENZEL J

Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus
JOURNAL OF CLINICAL MICROBIOLOGY
2007 vol. 45(6) pp. 2011-2013


Is throat screening necessary to detect methicillin-resistant Staphylococcus aureus colonization in patients upon admission to an intensive care unit?
JOURNAL OF CLINICAL MICROBIOLOGY
2007 vol. 45 pp. 1072-1073
HARBARTH S, SCHRENZEL J, RENZI G, AKAKPO C, RICOU B

Management of a large healthcare-associated outbreak of Panton-Valentine leucocidin-positive meticillin-resistant Staphylococcus aureus in Germany
JOURNAL OF HOSPITAL INFECTION
2007 vol. 67(2) pp. 114-120
WAGENLEHNER FM, NABER KG, BAMBL E, RAAB U, WAGENLEHNER C, KAHLAU D, HÖLLER C, WITTE W, WEIDNER W, LEHN N, HARBARTH S, LINDE HJ

A simulation-based evaluation of methods to estimate the impact of an adverse event on hospital length of stay
MEDICAL CARE
2007 vol. 45 pp. 108-115
SAMORE, MH, SHEN, S, GREENE, T, STODDARD, G, SAUER, B, SHINOGLE, J, NEBEKER, J, HARBARTH, S

Skin reactions related to hand hygiene and selection of hand hygiene products
AMERICAN JOURNAL OF INFECTION CONTROL
2006 vol. 34 pp. 627-635
LARSON E, GIRARD R, PESSOA-SILVA CL, BOYCE J, DONALDSON L, PITTET D

Evaluating the probability of previously unknown carriage of MRSA at hospital admission
AMERICAN JOURNAL OF MEDICINE
2006 vol. 119(3) pp. 275-275
HARBARTH S, SAX H, FANKHAUSER-RODRIGUEZ C, SCHRENZEL J, AGOSTINHO A, PITTET D

A randomized double-blind trial of iseganan in prevention of ventilator-associated pneumonia
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2006 vol. 173 pp. 91-97
KOLLEF M, PITTET D, GARCIA MS, CHASTRE J, FAGON JY, BONTEN M, HYZY R, FLEMING TR, FUCHS H, BELLM L, MERCAT A, MANEZ R, MARTINEZ A, EGGIMANN P, DAGUERRE M, LUYT CE

Procalcitonin Guidance of Antibiotic Therapy in Community-acquired Pneumonia: A Randomized Trial
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2006 vol. 174(1) pp. 84-93
CHRIST-CRAIN MIRJAM ET AL.

Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2006 vol. 174(1) pp. 84-93
CHRIST-CRAIN M, STOLZ D, BINGISSER R, MULLER CHRISTIAN, MIEDINGER D, HUBER PR, ZIMMERLI W, HARBARTH S, TAMM M, MÜLLER B

Navigating the world wide web in search of resources on antimicrobial resistance
CLINICAL INFECTIOUS DISEASES
2006 vol. 43 pp. 72-78
HARBARTH S, EMONET S

Reduction of urinary tract infection and antibiotic use after surgery: A controlled, prospective, befor after intervention study
CLINICAL INFECTIOUS DISEASES
2006 vol. 42 pp. 1544-1551
STEPHAN F, SAX H, WACHSMUTH M, HOFFMEYER P, CLERGUE F, PITTET D

Control of endemic methicillin-resistant Staphylococcus aureus - recent advances and future challenges
CLINICAL MICROBIOLOGY AND INFECTION
2006 vol. 12 pp. 1154-1162
HARBARTH S

Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study
CRITICAL CARE
2006 vol. 10 pp. 0-0
HARBARTH S, MASUET-AUMATELL C, SCHRENZEL J, FRANCOIS P, AKAKPO C, RENZI G, PUGIN J, RICOU B, PITTET D

Primary invasive aspergillosis of the digestive tract: report of two cases and review of the literature
INFECTION
2006 vol. 34(6) pp. 333-338
EGGIMANN PHILIPPE, CHEVROLET JEAN-CLAUDE, STAROBINSKI M, MAJNO PIETRO, TOTSCH MARTIN, CHAPUIS BERNARD, PITTET DIDIER

Outbreak of endophthalmitis after cataract surgery: the importance of the quality of the surgical wound
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2006 vol. 27(11) pp. 1246-1248
HUGONNET STEPHANE, DOSSO ANDRE, DHARAN SASI, MARTIN YVES, HERRERO MARIA-LUISA, REGNIER CAROLE, PITTET DIDIER

Challenging the world: patient safety and health care-associated infection
INTERNATIONAL JOURNAL FOR QUALITY IN HEALTH CARE
2006 vol. 18 pp. 4-8
PITTET D, DONALDSON L

Clean care is safer care': the Global Patient Safety Challenge 2005-2006
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
2006 vol. 10 pp. 419-424
PITTET D, ALLEGRANZI B, STORR J, DONALDSON L

Muslim health-care workers and alcohol-based handrubs
LANCET
2006 vol. 367 pp. 1025-1027
AHMED QA, MEMISH ZA, ALLEGRANZI B, PITTET D

Evidence-based model for hand transmission during patient care and the role of improved practices
LANCET INFECTIOUS DISEASES
2006 vol. 6(10) pp. 641-652
PITTET D, ALLEGRANZI B, SAX H, DHARAN S, PESSOA-SILVA CL, DONALDSON L, BOYCE JM

Postoperative fungal infections
SURGICAL INFECTIONS
2006 vol. 7 Suppl 2 pp. 53-56
EGGIMANN PHILIPPE, PITTET DIDIER

Treatment options of invasive fungal infections in adults
SWISS MEDICAL WEEKLY
2006 vol. 136 pp. 447-463
FLUCKIGER U, MARCHETTI O, BILLE J, EGGIMANN P, ZIMMERLI S, IMHOF A, GARBINO J, RUE C, PITTET D, TAUBER M, GLAUSER M, CALANDRA T

Prevalence and prediction of previously unknown MRSA carriage on admission to a geriatric hospital
AGE AND AGEING
2005 vol. 34 pp. 456-462
SAX HUGO, HARBARTH STEPHAN, GAVAZZI GAETAN, HENRY NICOLE, SCHRENZEL JACQUES, ROHNER PETER, MICHEL JEAN-PIERRE, PITTET DIDIER

Clean Care is safer care: the first global challenge of the WHO World Alliance for Patient Safety
AMERICAN JOURNAL OF INFECTION CONTROL
2005 vol. 33 pp. 476-479
PITTET DIDIER, DONALDSON L

Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses
AMERICAN JOURNAL OF INFECTION CONTROL
2005 vol. 33 pp. 558-560
ROTTER M, SATTAR SA, DHARAN S, WEBBER P, VOSS A, PITTET DIDIER

Infection control and quality health care in the new millenium
AMERICAN JOURNAL OF INFECTION CONTROL
2005 vol. 33 pp. 258-267
PITTET DIDIER

Long-term reduction of vascular access-associated bloodstream infection
ANNALS OF INTERNAL MEDICINE
2005 vol. pp. 875-876
EGGIMANN PHILIPPE, HUGONNET STEPHANE, SAX HUGO, HARBARTH STEPHAN, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Ethics roundtable debate: A patient dies from an ICU-acquired infection related to methicillin-resistant Staphylococcus aureus--how do you defend your case and your team?
CRITICAL CARE
2005 vol. 9(1) pp. 5-9
VINCENT JL, BRUN-BUISSON C, NIEDERMAN M, HAENNI C, HARBARTH S, SPRUMONT D, VALENCIA M, TORRES A

Mid-regional pro-adrenomedullin as a prognostic marker in sepsis: an observational study
CRITICAL CARE
2005 vol. 9 pp. 816-824
CHRIST-CRAIN M, MORGENTHALER NG, STRUCK J, HARBARTH STEPHAN, BERGMANN A, MULLER B

Antimicrobial resistance determinants and future control
EMERGING INFECTIOUS DISEASES (PRINT)
2005 vol. 11 pp. 794-801
HARBARTH STEPHAN, SAMORE MH

Community-associated methicillin-resistant Staphylococcus aureus, Switzerland
EMERGING INFECTIOUS DISEASES (PRINT)
2005 vol. 11 pp. 962-965
HARBARTH STEPHAN, FRANCOIS PATRICE, SCHRENZEL JACQUES, FANKHAUSER-RODRIGUEZ CAROLINA, HUGONNET STEPHANE, KOESSLER THIBAUD, HUYGHE ANTOINE, PITTET DIDIER

Lack of effect of antibiotic combination therapy on mortality in patients with pneumococcal sepsis
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2005 vol. pp. 688-690


Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2005 vol. 24 pp. 688-690
HARBARTH STEPHAN, GARBINO JORGE, PUGIN JEROME, ROMAND JACQUES-ANDRE, PITTET DIDIER

Knowledge of standard and isolation precautions in a large teaching hospital
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2005 vol. pp. 298-304
SAX HUGO, PERNEGER THOMAS, HUGONNET STEPHANE, HERRAULT PASCALE, CHRAITI MARIE-NOELLE, PITTET DIDIER

Attitudes and perceptions toward hand hygiene among healthcare workers caring for critically ill neonates
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26 pp. 305-311
PESSOA DA SILVA CARMEN, POSFAY-BARBE KLARA, PFISTER RICCARDO, TOUVENEAU SYLVIE, PERNEGER THOMAS, PITTET DIDIER

Clean Care is Safer Care: the first global challenge of the WHO World Alliance for Patient Safety
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26 pp. 891-894
PITTET DIDIER, DONALDSON L

Nosocomial bacteremia: clinical significance of a single blood culture positive for coagulase-negative staphylococci
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26(8) pp. 697-702
FAVRE BERTRAND, HUGONNET STEPHANE, CORREA FELIU LILIANA, SAX HUGO, ROHNER PETER, PITTET DIDIER

The impact of methicillin resistance in Staphylococcus aureus bacteremia on patient outcomes: mortality, length of stay, and hospital charges
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26(2) pp. 166-174
COSGROVE SE, QI Y, KAYE KS, HARBARTH S, KARCHMER AW, CARMELI Y

Invasive candidiasis: comparison of management choices by infectious disease and critical care specialists
INTENSIVE CARE MEDICINE
2005 vol. 31 pp. 1514-1521
GARBINO JORGE, PITTET DIDIER

Use of an automated multiple-locus, variable-number tandem repeat-based method for rapid and high-throughput genotyping of Staphylococcus aureus isolates
JOURNAL OF CLINICAL MICROBIOLOGY
2005 vol. 43 pp. 3346-3355
FRANCOIS PATRICE, HUYGHE ANTOINE, CHARBONNIER YVAN, BENTO MANUELA, HERZIG SEBASTIEN, TOPOLSKI IVAN, FLEURY BENEDICTE, LEW DANIEL, VAUDAUX PIERRE, HARBARTH STEPHAN, VAN LEEUWEN WILLEM, VAN BELKUM ALEX, BLANC D.S., PITTET DIDIER, SCHRENZEL JACQUES

Pasteurella multocida endophthalmitis: case report and review of the literature.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
2005 vol. 222(3) pp. 231-233
DANG BURGENER NP., BAGLIVO EDOARDO, HARBARTH STEPHAN, SAHABO CHRISTOPHE, PITTET DIDIER, SAFRAN AVINOAM

Clean Care is Safer Care: a worldwide priority
LANCET
2005 vol. 366 pp. 1246-1247
PITTET DIDIER, DONALDSON L

Clean hands reduce the burden of disease
LANCET
2005 vol. 366(9481) pp. 185-187
PITTET DIDIER

Considerations for a WHO European strategy on health-care-associated infection, surveillance, and control
LANCET INFECTIOUS DISEASES
2005 vol. 5(4) pp. 242-250
PITTET D. ET AL.

Meticillin-resistant Staphylococcus aureus
LANCET INFECTIOUS DISEASES
2005 vol. 5(10) pp. 653-663
BOYCE JM, COOKSON B, CHRISTIANSEN K, HORI S, VUOPIO-VARKILA J, KOCAGÖZ S, OZTOP AY, VANDENBROUCKE-GRAULS CM, HARBARTH S, PITTET D

Infection and rejection in liver transplant patients: a 10-year Swiss single-centre experience
SWISS MEDICAL WEEKLY
2005 vol. 135 pp. 587-593
GARBINO JORGE, ROMAND JACQUES-ANDRE, PITTET DIDIER, GIOSTRA EMILIANO, MENTHA GILLES, SUTER PETER M

Considerations for a WHO European strategy on health-care-associated infection, surveillance and control
THE LANCET INFECTIOUS DISEASES
2005 vol. 5 pp. 242-250
PITTET DIDIER, ALLENGRANZI B, SAX HUGO, BERTINATO L, CONCIA E, COOKSON B, FABRY J, RICHET H, PHILIP P, SPENCER RC, GANTER BW, LAZZARI S

Infection in breast implants
THE LANCET INFECTIOUS DISEASES
2005 vol. 5 pp. 94-106
PITTET-CUENOD BRIGITTE, MONTANDON DENYS, PITTET DIDIER

Consequences of an unsufficient range of immunity in "pediatric" infectious diseases--example with measles
THERAPEUTISCHE UMSCHAU : MONATSSCHRIFT FUER PRAKTISCHE MEDIZIN = REVUE THERAPEUTIQUE : REVUE MENSUELLE DE MEDECINE PRATIQUE
2005 vol. 62(10) pp. 679-684
UCKAY ILKER, SAX HUGO, HUGONNET STEPHANE, ARAMBURU C, BESSIRE N, RUTSCHMANN OLIVIER, KAISER LAURENT, GERVAIX ALAIN, SUDRE PHILIPPE, SIEGRIST CLAIRE-ANNE, PITTET DIDIER

Transmission of severe acute respiratory syndrome in critical care : Do we need a change ?
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2004 vol. 169 pp. 1177-1178
HUGONNET STEPHANE, PITTET DIDIER

Hand Hygiene among Physicians: performance, beliefs, and perceptions
ANNALS OF INTERNAL MEDICINE
2004 vol. 141 pp. 1-8
PITTET DIDIER, ANNE SIMON, HUGONNET STEPHANE, PESSOA DA SILVA CARMEN, SAUVAN VALERIE, PERNEGER THOMAS

A randomized clinical trial to compare fleroxacin-rifampicin with flucloxacillin or vancomycin for the treatment of staphylococcal infection
CLINICAL INFECTIOUS DISEASES
2004 vol. 39(9) pp. 1285-1292
SCHRENZEL JACQUES, HARBARTH STEPHAN, SCHOCKMEL G, GENNE DANIEL, BREGENZER T, FLUECKIGER U, PETIGNAT C, JACOBS F, FRANCIOLI P, ZIMMERLI W, LEW DANIEL

Epidemiology of candidemia in Swiss tertiary care hospitals: secular trends 1991-2000
CLINICAL INFECTIOUS DISEASES
2004 vol. 38 pp. 311-320
MARCHETTI O, BILLE J, FLUCKIGER U, EGGIMANN PHILIPPE, RUEF C, GARBINO JORGE, CALANDRA T, GLAUSER MP, TÄUBER M, PITTET DIDIER

Quantifying Uncertainty: Physicians' Estimates of Infection in Critically Ill Neonates and Children
CLINICAL INFECTIOUS DISEASES
2004 vol. 38 pp. 1383-1390
FISCHER JE, HARBARTH STEPHAN, AGTHE AG, BENN A, RINGER SA, GOLDMANN DA, FANCONI S

G-CSF and Il-8 for early diagnosis of sepsis in neotates and critically ill children - safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled tri al [ISRCTN91123847]
CRITICAL CARE
2004 vol. 8 pp. 443-450
HORISBERGER T, HARBARTH STEPHAN, NADAL D, BAENZIGER O, FISCHER JE

Adrenal insufficiency: the link between low apolipoprotein A-I levels and poor outcome in the critically ill?
CRITICAL CARE MEDICINE
2004 vol. 32 pp. 1978-1979
CHENAUD CATHERINE, MERLANI PAOLO, ROUX-LOMBARD-LATUNE PASCALE, BURGER DANIELLE, HARBARTH STEPHAN, LUYASU SAMUEL, GRAF JEAN-DANIEL, DAYER JEAN-MICHEL, RICOU BARA

Low apolipoprotein A-I level at intensive care unit admission and systemic inflammatory response syndrome exacerbation
CRITICAL CARE MEDICINE
2004 vol. 32 pp. 632-637
CHENAUD C, MERLANI P, ROUX LOMBARD P, BURGER D, HARBARTH S, LUYASU S, GRAF JD, DAYER JM, RICOU B

Nursing resources: a major determinant of nosocomial infection ?
CURRENT OPINION IN INFECTIOUS DISEASES
2004 vol. 17 pp. 329-333
HUGONNET STEPHANE, HARBARTH STEPHAN, SAX HUGO, DUNCAN R, PITTET DIDIER

Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes
EMERGING INFECTIOUS DISEASES (PRINT)
2004 vol. 10 pp. 514-517
ALBRICH WC, MONNET DL, HARBARTH STEPHAN

Nosocomial bloodstream infection and clinical sepsis
EMERGING INFECTIOUS DISEASES (PRINT)
2004 vol. 10 pp. 76-81
HUGONNET STEPHANE, SAX HUGO, EGGIMANN PHILIPPE, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Are there patients with Peritonitis Who Require Empiric Therapy for Enterococcus
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2004 vol. 23 pp. 73-77
HARBARTH STEPHAN, UCKAY I

An outbreak of Pseudomonas Aeruginosa Pneumonia and Bloodstream Infection Associated With Intermittent Otitis Externa in a Healthcar Worker
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. 25 pp. 1083-1089
ZAWACKI A, O'ROURKE E, POTTER-BYNOE G, MACONE A, HARBARTH STEPHAN, GOLDMANN D

Dynamics of bacterial hand contamination during routine neonatal care
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. 25 pp. 192-197
PESSOA DA SILVA CARMEN, DHARAN SASI, HUGONNET STEPHANE, TOUVENEAU S, POSFAY-BARBE KLARA, PFISTER RICCARDO, PITTET DIDIER

Impact of ventilator -associated pneumonia on resource utilization and patient outcome
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. pp. 1090-1096
HUGONNET STEPHANE, EGGIMANN PHILIPPE, BORST FRANCOIS, PATRICE MARICOT, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Reply to letter by Tulleken et al.
INTENSIVE CARE MEDICINE
2004 vol. 30 pp. 998-999
EGGIMANN PHILIPPE, HUGONNET STEPHANE, SAX HUGO, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Semmelweis' legacy: insights from an international survey among 265,000 students in 32 countries
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
2004 vol. 207 pp. 1-5
HARBARTH STEPHAN, ALBRICH W, PITTET DIDIER

Semmelweis' legacy: insights from an international survey among 265,000 students in 32 countries
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
2004 vol. 207(5) pp. 481-485
HARBARTH S, ALBRICH W, PITTET D

A novel multiplex real-time PCR assay for rapid typing of major staphylococcal cassette chromosome mec elements
JOURNAL OF CLINICAL MICROBIOLOGY
2004 vol. 42 pp. 3309-3312
FRANCOIS PATRICE, RENZI GESUELE, PITTET DIDIER, BENTO MANUELA, LEW DANIEL, HARBARTH STEPHAN, VAUDAUX PIERRE, SCHRENZEL JACQUES

The Lowbury lecture: behaviour in infection control
JOURNAL OF HOSPITAL INFECTION
2004 vol. 58 pp. 1-13
PITTET DIDIER

Is anti-tumor necrosis factor therapy associated with increased mortality in patients with severe sepsis caused by pneumonia ?
JOURNAL OF INFECTIOUS DISEASES
2004 vol. 189 pp. 1743-1743
HARBARTH S, GARBINO J, PITTET D, PUGIN J

Is anti-tumor necrosis factor therapy associated with increased mortality in patients with severe sepsis caused by pneumonia?
JOURNAL OF INFECTIOUS DISEASES
2004 vol. pp. 1743-1743
HARBARTH STEPHAN, GARBINO JORGE, PITTET DIDIER, PUGIN JEROME

Comparative analysis and validation of different assays for glycopeptide susceptibility among methicillin-resistant staphylococcus aureus strains
JOURNAL OF MICROBIOLOGICAL METHODS
2004 vol. 57 pp. 231-239
BERNARD L, VAUDAUX P, ROHNER P, HUGGLER E, ARMANET M, PITTET D, LEW DP, SCHRENZEL J

Effect of a comprehensive, multidisciplinary, educational program on the use of antibiotics in a Geriatric University Hospital
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY
2004 vol. 52 pp. 112-116
LUTTERS M, HARBARTH STEPHAN, JANSSENS JEAN-PAUL, FREUDIGER H, HERRMANN FRANCOIS, MICHEL JEAN-PIERRE, VOGT NICOLE

Clean hands reduce the burden of disease
LANCET
2004 vol. 366 pp. 185-187
PITTET DIDIER

Catheter-related infections
MICROBES AND INFECTION : A JOURNAL ON INFECTIOUS AGENTS AND HOST DEFENSES
2004 vol. 6 pp. 1033-1042
EGGIMANN PHILIPPE, SAX HUGO, PITTET DIDIER

Enjeux, stratégie de traitement et évolution clinique des bactérémies à SARM
PRESSE MEDICALE (DES 1983)
2004 vol. 12 pp. 10-17
PITTET DIDIER

Risk factors for persistent carriage of methicillin resistant Staphylococcus aureus
CLINICAL INFECTIOUS DISEASES.
2000 vol. 31(6) pp. 1380-1385
HARBARTH S, LIASSINE N, DHARAN S, HERRAULT P, AUCKENTHALER R, PITTET D

Randomized, placebo-controlled, double-blind trial to evaluate the efficacy of mupirocin for eradicating carriage of methicillin-resistant Staphylococcus aureus
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
1999 vol. 43(6) pp. 1412-1416
HARBARTH S, DHARAN S, LIASSINE N, COPIN P, AUCKENTHALER R, PITTET D

Impact of methicillin resistance on the outcome of patients with bacteremia caused by Staphylococcus aureus
ARCHIVES OF INTERNAL MEDICINE
1998 vol. 158 pp. 182-189
HARBARTH STEPHAN, RUTSCHMANN OLIVIER, SUDRE PHILIPPE, PITTET DIDIER


Research's domains