Harbarth S/Pittet D  CV du Chef de Groupe  Composition du Groupe

  Coordonnées du groupe

Pr. Pittet Didier
HUG/Spécialités de Médecine
Serv Mal. infec. Bat Séminaire
Rue Gabrielle-Perret-Gentil 4
1211 Genève 14
Suisse

Didier.Pittet@hcuge.ch

Tél.: 022/372.98.44
Fax: 022/372.39.87




Commentaires



Pages générées le 17.11.2015
Sujet de recherche | Publications du groupe | Domaines de recherche

MRSA

Nature du problème
Depuis plusieurs années, des infections causées par des souches de staphylocoques dorés résistants à la méthicilline (MRSA) et souvent multi-résistants ont été signalées partout dans le monde. La prévalence de l'infection varie entre 0 et 50 %; elle est plus élevée dans les hôpitaux universitaires, en Suisse comme ailleurs.
Situation aux HUG
MRSA est un problème aux HUG depuis le début des années 90, en proportion épidémique depuis 1993-1994. Des efforts de contrôle ont été instaurés, avec succès. Malheureusement, nous assistons depuis le milieu de l'année 1999 à une nouvelle augmentation du nombre de cas, qui prend des proportions inquiétantes depuis 2000. Cette épidémie touche tous les secteurs del'institution, à des degrés variables. L'augmentation de l'incidence est attribuée en partie à l'augmentation du réservoir épidémique de provenance extérieure aux HUG.
Pourquoi ce problème nous inquiète-t-il ?
Les infections à MRSA sont grevées d'un taux important de morbidité et de mortalité. Elles viennent s'ajouter aux autres infections nosocomiales; leur traitement impose le recours à des antibiotiques relativement toxiques, pourvus d'effets secondaires et nécessitant des examens complémentaires pour assurer leur bonne utilisation. Enfin, la transmission intra-hospitalière est le reflet d'un manque de qualité des soins.
Prévention
Les principales mesures de lutte contre la propagation de l'infection sont l'hygiène des mains, l'identification des patients colonisés ou infectés, les mesures d'isolement destinées à protéger le milieu hospitalier, les précautions lors de transferts, et la réduction du portage.
Projets de recherche clinique
1) Identification du réservoir
Les objectifs sont : a) recueillir des informations épidémiologiques permettant une lutte globale et une action sur tous les réservoirs de l'épidémie ; b) accélérer la prise en charge et permettre l'orientation optimale des patients porteurs dès l'admission, ainsi que la détection des cas d'entourage ; c) optimaliser l''occupation des chambres d'isolement en ne les utilisant que pour des cas confirmés.
2) Prévention des infections à MRSA aux soins intensifs et mise en place d'un test ultra-rapide
Les objectifs sont : a) accélérer la prise en charge et permettre l'isolement précoce de patients colonisés; b) diminuer les taux de transmission croisée et d'infections graves à MRSA.
3) Evaluation retrospective de l'épidémie à MRSA aux HUG
L'objectif principal est de mieux comprendre les facteurs qui ont favorisé l'augmentation du nombre de cas MRSA depuis 2000 avec analyse épidémiologique et moléculaire de différentes souches MRSA isolées aux HUG.




Publications du groupe

Religion and culture: potential undercurrents influencing hand hygiene promotion in health care.
AMERICAN JOURNAL OF INFECTION CONTROL
2009 vol. 37(1) pp. 28-34
ALLEGRANZI B. AND AL.

The World Health Organization hand hygiene observation method.
AMERICAN JOURNAL OF INFECTION CONTROL
2009 vol. 37(10) pp. 827-834
SAX H, ALLEGRANZI B, CHRAITI MN, BOYCE J, LARSON E, PITTET D

Foreign body infections due to Staphylococcus epidermidis.
ANNALS OF MEDICINE
2009 vol. 41(2) pp. 109-119
UCKAY I, PITTET D, VAUDAUX P, SAX H, LEW D, WALDVOGEL FA

Community-associated methicillin-resistant Staphylococcus aureus: risk factors for infection, and long-term follow-up.
CLINICAL MICROBIOLOGY AND INFECTION
2009 vol. 15(6) pp. 552-559
LONGTIN Y, SUDRE P, FRANCOIS P, SCHRENZEL J, ARAMBURU C, PASTOR R, GERVAIX A, RENZI G, PITTET D, HARBARTH S

Impact of a prevention strategy targeting hand hygiene and catheter care on the incidence of catheter-related bloodstream infections.
CRITICAL CARE MEDICINE
2009 vol. 37(7) pp. 2167-2173
ZINGG W, IMHOF A, MAGGIORINI M, STOKER R, KELLER E, RUEF C

Cockroaches (Ectobius vittiventris) in an intensive care unit, Switzerland.
EMERGING INFECTIOUS DISEASES (PRINT)
2009 vol. 15(3) pp. 496-497
UCKAY I, SAX H, LONGET-DI PIETRO S, BAUR H, BOULC'H MF, AKAKPO C, CHEVROLET JC, PITTET D

Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: an interaction study in healthy volunteers.
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
2009 vol. 65(10) pp. 999-1006
CORTI N, HECK A, RENTSCH K, ZINGG W, STIEGER B, PAULI-MAGNUS C

Nurses and physicians' perceptions of the importance and impact of healthcare-associated infections and hand hygiene: a multi-center exploratory study in Hong Kong.
INFECTION
2009 vol. 37(4) pp. 320-333
TAI JWM, MOK ESB, CHING PTY, SETO WH, PITTET D

Evaluation of patients' mask use after the implementation of cough etiquette in the emergency department.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2009 vol. 30(9) pp. 904-908
LONGTIN Y, AKAKPO C, RUTSCHMANN O, PITTET D, SAX H

Patients' beliefs and perceptions of their participation to increase healthcare worker compliance with hand hygiene.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2009 vol. 30(9) pp. 830-839
LONGTIN Y, SAX H, ALLEGRANZI B, HUGONNET S, PITTET D

The World Health Organization Guidelines on Hand Hygiene in Health Care and their consensus recommendations.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2009 vol. 30(7) pp. 611-622
PITTET D. AND AL.

Defining, treating and preventing hospital acquired pneumonia: European perspective.
INTENSIVE CARE MEDICINE
2009 vol. 35(1) pp. 9-29
TORRES A. AND AL.

Peripheral venous catheters: an under-evaluated problem.
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
2009 vol. 34 pp. 38-42
ZINGG W, PITTET D

Pluripotent stem cells as new drugs? The example of Parkinson's disease
INTERNATIONAL JOURNAL OF PHARMACEUTICS
2009 vol. 381(2) pp. 113-121
PREYNAT-SEAUVE O, BURKHARD PR, VILLARD J, ZINGG W, GINOVART N, FEKI A, DUBOIS-DAUPHIN M, HURST S, MAURON A, JACONI M, KRAUSE KH

Preventing catheter-related bloodstream infections: thinking outside the checklist.
JAMA
2009 vol. 301(12) pp. 1285-1287
PERENCEVICH EN, PITTET D

Comparison of national and subnational guidelines for hand hygiene.
JOURNAL OF HOSPITAL INFECTION
2009 vol. 72(3) pp. 202-210
COOKSON B, MATHAI E, ALLEGRANZI B, PESSOA-SILVA CL, BAGHERI NEJAD S, SCHNEIDER A, TSCHOPP C, WENDT C, PITTET D

Hospital-wide surveillance of catheter-related bloodstream infection: from the expected to the unexpected.
JOURNAL OF HOSPITAL INFECTION
2009 vol. 73(1) pp. 41-46
ZINGG W, SAX H, INAN C, CARTIER V, DIBY M, CLERGUE F, PITTET D, WALDER B

Methods to evaluate the microbicidal activities of hand-rub and hand-wash agents.
JOURNAL OF HOSPITAL INFECTION
2009 vol. 73(3) pp. 191-199
ROTTER M, SATTAR SA, DHARAN S, ALLEGRANZI B, MATHAI E, PITTET D

Role of hand hygiene in healthcare-associated infection prevention.
JOURNAL OF HOSPITAL INFECTION
2009 vol. 73(4) pp. 305-315
ALLEGRANZI B, PITTET D

Surveillance of extended-spectrum-beta-lactamase-producing Enterobacteriaceae in a Swiss Tertiary Care Hospital.
SWISS MEDICAL WEEKLY
2009 vol. 139(51-52) pp. 747-751
FANKHAUSER C, ZINGG W, FRANCOIS P, DHARAN S, SCHRENZEL J, PITTET D, HARBARTH S

Rapid colonization with methicillin-resistant coagulase-negative staphylococci after surgery.
WORLD JOURNAL OF SURGERY
2009 vol. 33(10) pp. 2058-2062
ZINGG W, IMHOF A, SENN G, DEMARTINES N, RUEF C

Re: help or hindrance? Is current infection control advice applicable in low- and middle-income countries? A review of the literature.
AMERICAN JOURNAL OF INFECTION CONTROL
2008 vol. 36(7) pp. 499-501
STORR J, PITTET D

Novel microarray design strategy to study complex bacterial communities.
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
2008 vol. 74(6) pp. 1876-1885
HUYGHE ANTOINE, FRANCOIS P, CHARBONNIER YVAN, BENTO M, BONETTI EJ, PASTER BJ, BOLIVAR I, BARATTI-MAYER D, PITTET D, SCHRENZEL J

Ventilator-associated pneumonia as a quality indicator for patient safety?
CLINICAL INFECTIOUS DISEASES
2008 vol. 46(4) pp. 557-563
UCKAY ILKER, AHMED QA, SAX H, PITTET D

Healthcare-associated infections: think globally, act locally.
CLINICAL MICROBIOLOGY AND INFECTION
2008 vol. 14(10) pp. 895-907
MARCEL JP AND AL.

Healthcare-associated infections in neonates.
CURRENT OPINION IN INFECTIOUS DISEASES
2008 vol. 21(3) pp. 228-234
ZINGG W, POSFAY-BARBE KLARA, PITTET D

Methicillin-resistant Staphylococcus aureus, Geneva, Switzerland, 1993-2005.
EMERGING INFECTIOUS DISEASES (PRINT)
2008 vol. 14(2) pp. 304-307
FRANCOIS P, HARBARTH S, HUYGHE ANTOINE, RENZI G, BENTO M, GERVAIX A, PITTET D, SCHRENZEL J

Commentary: hand hygiene: it's all about when and how.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2008 vol. 29(10) pp. 957-959
PITTET D

Trial of alcohol-based hand gel in critical care units.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2008 vol. 29(6) pp. 577-579
MERMEL LA, BOYCE JM, VOSS A, ALLEGRANZI B, PITTET D

Effect of screening for methicillin-resistant Staphylococcus aureus carriage by polymerase chain reaction on the duration of unnecessary preemptive contact isolation.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2008 vol. 29(11) pp. 1077-1079
UCKAY ILKER, SAX H, ITEN A, CAMUS V, RENZI G, SCHRENZEL J, PERRIER A, PITTET D

Risk factors for methicillin-resistant Staphylococcus aureus surgical site infection.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2008 vol. 29(9) pp. 890-893
HARBARTH S, HUTTNER B, GERVAZ P, FANKHAUSER C, CHRAITI MARIE-NOELLE, SCHRENZEL J, LICKER M, PITTET D

Universal screening for methicillin-resistant Staphylococcus aureus at hospital admission and nosocomial infection in surgical patients.
JAMA
2008 vol. 299(10) pp. 1149-1157
HARBARTH S, FANKHAUSER C, SCHRENZEL J, CHRISTENSON JAN, GERVAZ P, BANDIERA-CLERC C, RENZI G, VERNAZ N, SAX H, PITTET D

Antibiotic prophylaxis before invasive dental procedures in patients with arthroplasties of the hip and knee.
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME
2008 vol. 90(7) pp. 833-838
UCKAY ILKER, PITTET D, BERNARD L, LEW D, PERRIER A, PETER R

Infection control as a major World Health Organization priority for developing countries.
JOURNAL OF HOSPITAL INFECTION
2008 vol. ;68(4) pp. 285-292
PITTET D, ALLEGRANZI B, STORR J, BAGHERI NEJAD S, DZIEKAN G, LEOTSAKOS A, DONALDSON L

Multi-resistant infections in repatriated patients after natural disasters: lessons learned from the 2004 tsunami for hospital infection control.
JOURNAL OF HOSPITAL INFECTION
2008 vol. 68(1) pp. 1-8
UCKAY ILKER, SAX H, HARBARTH S, BERNARD L, PITTET D

Rapid and high-throughput genotyping of Staphylococcus epidermidis isolates by automated multilocus variable-number of tandem repeats: a tool for real-time epidemiology.
JOURNAL OF MICROBIOLOGICAL METHODS
2008 vol. 72(3) pp. 296-305
FRANCOIS P, HOCHMANN A, HUYGHE ANTOINE, BONETTI EJ, RENZI G, HARBARTH S, KLINGENBERG C, PITTET D, SCHRENZEL J

A predictive model for identifying surgical patients at risk of methicillin-resistant Staphylococcus aureus carriage on admission.
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS
2008 vol. 207(5) pp. 683-689
HARBARTH S, SAX H, UCKAY I, FANKHAUSER C, AGOSTINHO A, CHRISTENSON JT, RENZI G, SCHRENZEL J, PITTET D

Preventing infections acquired during health-care delivery.
LANCET
2008 vol. 372(9651) pp. 1719-1720
PITTET D, ALLEGRANZI B

Alcohol-based rubs for hand antisepsis.
LANCET INFECTIOUS DISEASES
2008 vol. 8(10) pp. 585-586
PITTET D, DHARAN S

Infection control in paediatrics.
LANCET INFECTIOUS DISEASES
2008 vol. ;8(1) pp. 19-31
POSFAY-BARBE, ZERR DM, PITTET D

Cefuroxime prophylaxis is effective in noninstrumented spine surgery: a double-blind, placebo-controlled study.
SPINE
2008 vol. 33(18) pp. 1919-1924
PETIGNAT C AND AL.

Comment on: Control of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae using a computer-assisted management program to restrict third-generation cephalosporin use.
THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2008 vol. 62(5) pp. 1165-1165
HUTTNER B, PITTET D, HARBARTH S

Temporal effects of antibiotic use and hand rub consumption on the incidence of MRSA and Clostridium difficile.
THE JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
2008 vol. 62(3) pp. 601-607
VERNAZ N, SAX H, PITTET D, BONNABRY P, SCHRENZEL J, HARBARTH S

Age limit does not replace serologic testing for determination of immune status for measles
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2007 vol. 28 pp. 1117-1120
UCKAY I, HUGONNET S, KAISER L, SAX HG, PITTET D

Determinants of good adherence to hand hygiene among healthcare workers who have extensive exposure to hand hygiene campaigns
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2007 vol. 28(11) pp. 1267-1274
SAX H, UÇKAY I, RICHET H, ALLEGRANZI B, PITTET D

Double-blind, randomized, crossover trial of 3 hand rub formulations: fast-track evaluation of tolerability and acceptability
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2007 vol. 28(12) pp. 1344-1351
PITTET D, ALLEGRANZI B, SAX H, CHRAITI MN, GRIFFITHS W, RICHET H, WORLD HEALT ORG.

Evaluation of three molecular assays for rapid identification of methicillin-resistant Staphylococcus aureus
JOURNAL OF CLINICAL MICROBIOLOGY
2007 vol. 45 pp. 2011-2013
FRANCOIS P, BENTO M, RENZI G, HARBARTH S, PITTET D, SCHRENZEL J

Behavioural considerations for hand hygiene practices: the basic building blocks
JOURNAL OF HOSPITAL INFECTION
2007 vol. 65 pp. 1-8
WHITBY, M, PESSOA-SILVA, CL, MCLAWS, M, ALLEGRANZI, B, SAX, H, LARSON, E, SETO, WH, DONALDSON, L, PITTET, D

My five moments for hand hygiene': a user-centred design approach to understand, train, monitor and report hand hygiene
JOURNAL OF HOSPITAL INFECTION
2007 vol. 67 pp. 9-21
SAX H, ALLEGRANZI B, UCKAY I, LARSON E, BOYCE J, PITTET D

Skin reactions related to hand hygiene and selection of hand hygiene products
AMERICAN JOURNAL OF INFECTION CONTROL
2006 vol. 34 pp. 627-635
LARSON E, GIRARD R, PESSOA-SILVA CL, BOYCE J, DONALDSON L, PITTET D

Evaluating the probability of previously unknown carriage of MRSA at hospital admission
AMERICAN JOURNAL OF MEDICINE
2006 vol. 119(3) pp. 275-275
HARBARTH S, SAX H, FANKHAUSER-RODRIGUEZ C, SCHRENZEL J, AGOSTINHO A, PITTET D

A randomized double-blind trial of iseganan in prevention of ventilator-associated pneumonia
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2006 vol. 173 pp. 91-97
KOLLEF M, PITTET D, GARCIA MS, CHASTRE J, FAGON JY, BONTEN M, HYZY R, FLEMING TR, FUCHS H, BELLM L, MERCAT A, MANEZ R, MARTINEZ A, EGGIMANN P, DAGUERRE M, LUYT CE

Procalcitonin Guidance of Antibiotic Therapy in Community-acquired Pneumonia: A Randomized Trial
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2006 vol. 174(1) pp. 84-93
CHRIST-CRAIN MIRJAM ET AL.

Recurrent bacteremia with Helicobacter cinaedi: case report and review of the literature
BMC INFECTIOUS DISEASES
2006 vol. 6 pp. 86-86
UCKAY I, GARBINO J, DIETRICH PY, NINET B, ROHNER P, JACOMO V

Reduction of urinary tract infection and antibiotic use after surgery: A controlled, prospective, befor after intervention study
CLINICAL INFECTIOUS DISEASES
2006 vol. 42 pp. 1544-1551
STEPHAN F, SAX H, WACHSMUTH M, HOFFMEYER P, CLERGUE F, PITTET D

Evaluation of rapid screening and pre-emptive contact isolation for detecting and controlling methicillin-resistant Staphylococcus aureus in critical care: an interventional cohort study
CRITICAL CARE
2006 vol. 10 pp. 0-0
HARBARTH S, MASUET-AUMATELL C, SCHRENZEL J, FRANCOIS P, AKAKPO C, RENZI G, PUGIN J, RICOU B, PITTET D

Increased incidence of sexually transmitted infections in Geneva, Switzerland
DERMATOLOGY--
2006 vol. 212 pp. 41-46
ABRAHAM S, TOUTOUS-TRELLU L, PECHERE M, HUGONNET S, LIASSINE N, YERLY S, ROHNER P, NINET B, HIRSCHEL B, PIGUET V

Primary invasive aspergillosis of the digestive tract: report of two cases and review of the literature
INFECTION
2006 vol. 34(6) pp. 333-338
EGGIMANN PHILIPPE, CHEVROLET JEAN-CLAUDE, STAROBINSKI M, MAJNO PIETRO, TOTSCH MARTIN, CHAPUIS BERNARD, PITTET DIDIER

Outbreak of endophthalmitis after cataract surgery: the importance of the quality of the surgical wound
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2006 vol. 27(11) pp. 1246-1248
HUGONNET STEPHANE, DOSSO ANDRE, DHARAN SASI, MARTIN YVES, HERRERO MARIA-LUISA, REGNIER CAROLE, PITTET DIDIER

Challenging the world: patient safety and health care-associated infection
INTERNATIONAL JOURNAL FOR QUALITY IN HEALTH CARE
2006 vol. 18 pp. 4-8
PITTET D, DONALDSON L

Clean care is safer care': the Global Patient Safety Challenge 2005-2006
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
2006 vol. 10 pp. 419-424
PITTET D, ALLEGRANZI B, STORR J, DONALDSON L

Rapid Staphylococcus aureus agr type determination by a novel multiplex real-time quantitative PCR assay
JOURNAL OF CLINICAL MICROBIOLOGY
2006 vol. 44 pp. 1892-1895
FRANCOIS P, KOESSLER T, HUYGHE A, HARBARTH S, BENTO M, LEW D, ETIENNE J, PITTET D, SCHRENZEL J

Recurrent osteomyelitis caused by infection with different bacterial strains without obvious source of reinfection
JOURNAL OF CLINICAL MICROBIOLOGY
2006 vol. 44(3) pp. 1194-1196
UÇKAY ILKER, ASSAL MATHIEU, LEGOUT LAURENCE, ROHNER PETER, STERN RICHARD, LEW DANIEL, HOFFMEYER PIERRE, BERNARD LOUIS

Use of oligoarrays for characterization of community-onset methicillin-resistant Staphylococcus aureus
JOURNAL OF CLINICAL MICROBIOLOGY
2006 vol. 44 pp. 1040-1048
KOESSLER T, FRANCOIS P, CHARBONNIER Y, HUYGHE A, BENTO M, DHARAN S, RENZI G, LEW D, HARBARTH S, PITTET D, SCHRENZEL J

Control of a cluster of community-associated, methicillin-resistant Staphylocloccus aureus in neonatology
JOURNAL OF HOSPITAL INFECTION
2006 vol. 63 pp. 93-100
SAX H, POSFAY-BARBE K, HARBARTH S, FRANCOIS P, TOUVENEAU S, PESSOA-SILVA CL, SCHRENZEL J, DHARAN S, GERVAIX A, PITTET D

Muslim health-care workers and alcohol-based handrubs
LANCET
2006 vol. 367 pp. 1025-1027
AHMED QA, MEMISH ZA, ALLEGRANZI B, PITTET D

Evidence-based model for hand transmission during patient care and the role of improved practices
LANCET INFECTIOUS DISEASES
2006 vol. 6(10) pp. 641-652
PITTET D, ALLEGRANZI B, SAX H, DHARAN S, PESSOA-SILVA CL, DONALDSON L, BOYCE JM

Postoperative fungal infections
SURGICAL INFECTIONS
2006 vol. 7 Suppl 2 pp. 53-56
EGGIMANN PHILIPPE, PITTET DIDIER

Treatment options of invasive fungal infections in adults
SWISS MEDICAL WEEKLY
2006 vol. 136 pp. 447-463
FLUCKIGER U, MARCHETTI O, BILLE J, EGGIMANN P, ZIMMERLI S, IMHOF A, GARBINO J, RUE C, PITTET D, TAUBER M, GLAUSER M, CALANDRA T

Prevalence and prediction of previously unknown MRSA carriage on admission to a geriatric hospital
AGE AND AGEING
2005 vol. 34 pp. 456-462
SAX HUGO, HARBARTH STEPHAN, GAVAZZI GAETAN, HENRY NICOLE, SCHRENZEL JACQUES, ROHNER PETER, MICHEL JEAN-PIERRE, PITTET DIDIER

Clean Care is safer care: the first global challenge of the WHO World Alliance for Patient Safety
AMERICAN JOURNAL OF INFECTION CONTROL
2005 vol. 33 pp. 476-479
PITTET DIDIER, DONALDSON L

Comparative efficacy of hand hygiene agents in the reduction of bacteria and viruses
AMERICAN JOURNAL OF INFECTION CONTROL
2005 vol. 33 pp. 558-560
ROTTER M, SATTAR SA, DHARAN S, WEBBER P, VOSS A, PITTET DIDIER

Infection control and quality health care in the new millenium
AMERICAN JOURNAL OF INFECTION CONTROL
2005 vol. 33 pp. 258-267
PITTET DIDIER

Long-term reduction of vascular access-associated bloodstream infection
ANNALS OF INTERNAL MEDICINE
2005 vol. pp. 875-876
EGGIMANN PHILIPPE, HUGONNET STEPHANE, SAX HUGO, HARBARTH STEPHAN, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Community-associated methicillin-resistant Staphylococcus aureus, Switzerland
EMERGING INFECTIOUS DISEASES (PRINT)
2005 vol. 11 pp. 962-965
HARBARTH STEPHAN, FRANCOIS PATRICE, SCHRENZEL JACQUES, FANKHAUSER-RODRIGUEZ CAROLINA, HUGONNET STEPHANE, KOESSLER THIBAUD, HUYGHE ANTOINE, PITTET DIDIER

Lack of effect of combination antibiotic therapy on mortality in patients with pneumococcal sepsis.
EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES
2005 vol. 24 pp. 688-690
HARBARTH STEPHAN, GARBINO JORGE, PUGIN JEROME, ROMAND JACQUES-ANDRE, PITTET DIDIER

Knowledge of standard and isolation precautions in a large teaching hospital
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
2005 vol. pp. 298-304
SAX HUGO, PERNEGER THOMAS, HUGONNET STEPHANE, HERRAULT PASCALE, CHRAITI MARIE-NOELLE, PITTET DIDIER

Attitudes and perceptions toward hand hygiene among healthcare workers caring for critically ill neonates
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26 pp. 305-311
PESSOA DA SILVA CARMEN, POSFAY-BARBE KLARA, PFISTER RICCARDO, TOUVENEAU SYLVIE, PERNEGER THOMAS, PITTET DIDIER

Clean Care is Safer Care: the first global challenge of the WHO World Alliance for Patient Safety
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26 pp. 891-894
PITTET DIDIER, DONALDSON L

Nosocomial bacteremia: clinical significance of a single blood culture positive for coagulase-negative staphylococci
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2005 vol. 26(8) pp. 697-702
FAVRE BERTRAND, HUGONNET STEPHANE, CORREA FELIU LILIANA, SAX HUGO, ROHNER PETER, PITTET DIDIER

Invasive candidiasis: comparison of management choices by infectious disease and critical care specialists
INTENSIVE CARE MEDICINE
2005 vol. 31 pp. 1514-1521
GARBINO JORGE, PITTET DIDIER

Use of an automated multiple-locus, variable-number tandem repeat-based method for rapid and high-throughput genotyping of Staphylococcus aureus isolates
JOURNAL OF CLINICAL MICROBIOLOGY
2005 vol. 43 pp. 3346-3355
FRANCOIS PATRICE, HUYGHE ANTOINE, CHARBONNIER YVAN, BENTO MANUELA, HERZIG SEBASTIEN, TOPOLSKI IVAN, FLEURY BENEDICTE, LEW DANIEL, VAUDAUX PIERRE, HARBARTH STEPHAN, VAN LEEUWEN WILLEM, VAN BELKUM ALEX, BLANC D.S., PITTET DIDIER, SCHRENZEL JACQUES

Pasteurella multocida endophthalmitis: case report and review of the literature.
KLINISCHE MONATSBLATTER FUR AUGENHEILKUNDE
2005 vol. 222(3) pp. 231-233
DANG BURGENER NP., BAGLIVO EDOARDO, HARBARTH STEPHAN, SAHABO CHRISTOPHE, PITTET DIDIER, SAFRAN AVINOAM

Clean Care is Safer Care: a worldwide priority
LANCET
2005 vol. 366 pp. 1246-1247
PITTET DIDIER, DONALDSON L

Clean hands reduce the burden of disease
LANCET
2005 vol. 366(9481) pp. 185-187
PITTET DIDIER

Considerations for a WHO European strategy on health-care-associated infection, surveillance, and control
LANCET INFECTIOUS DISEASES
2005 vol. 5(4) pp. 242-250
PITTET D. ET AL.

Meticillin-resistant Staphylococcus aureus
LANCET INFECTIOUS DISEASES
2005 vol. 5(10) pp. 653-663
BOYCE JM, COOKSON B, CHRISTIANSEN K, HORI S, VUOPIO-VARKILA J, KOCAGÖZ S, OZTOP AY, VANDENBROUCKE-GRAULS CM, HARBARTH S, PITTET D

Infection and rejection in liver transplant patients: a 10-year Swiss single-centre experience
SWISS MEDICAL WEEKLY
2005 vol. 135 pp. 587-593
GARBINO JORGE, ROMAND JACQUES-ANDRE, PITTET DIDIER, GIOSTRA EMILIANO, MENTHA GILLES, SUTER PETER M

Considerations for a WHO European strategy on health-care-associated infection, surveillance and control
THE LANCET INFECTIOUS DISEASES
2005 vol. 5 pp. 242-250
PITTET DIDIER, ALLENGRANZI B, SAX HUGO, BERTINATO L, CONCIA E, COOKSON B, FABRY J, RICHET H, PHILIP P, SPENCER RC, GANTER BW, LAZZARI S

Infection in breast implants
THE LANCET INFECTIOUS DISEASES
2005 vol. 5 pp. 94-106
PITTET-CUENOD BRIGITTE, MONTANDON DENYS, PITTET DIDIER

Consequences of an unsufficient range of immunity in "pediatric" infectious diseases--example with measles
THERAPEUTISCHE UMSCHAU : MONATSSCHRIFT FUER PRAKTISCHE MEDIZIN = REVUE THERAPEUTIQUE : REVUE MENSUELLE DE MEDECINE PRATIQUE
2005 vol. 62(10) pp. 679-684
UCKAY ILKER, SAX HUGO, HUGONNET STEPHANE, ARAMBURU C, BESSIRE N, RUTSCHMANN OLIVIER, KAISER LAURENT, GERVAIX ALAIN, SUDRE PHILIPPE, SIEGRIST CLAIRE-ANNE, PITTET DIDIER

Transmission of severe acute respiratory syndrome in critical care : Do we need a change ?
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
2004 vol. 169 pp. 1177-1178
HUGONNET STEPHANE, PITTET DIDIER

Hand Hygiene among Physicians: performance, beliefs, and perceptions
ANNALS OF INTERNAL MEDICINE
2004 vol. 141 pp. 1-8
PITTET DIDIER, ANNE SIMON, HUGONNET STEPHANE, PESSOA DA SILVA CARMEN, SAUVAN VALERIE, PERNEGER THOMAS

Epidemiology of candidemia in Swiss tertiary care hospitals: secular trends 1991-2000
CLINICAL INFECTIOUS DISEASES
2004 vol. 38 pp. 311-320
MARCHETTI O, BILLE J, FLUCKIGER U, EGGIMANN PHILIPPE, RUEF C, GARBINO JORGE, CALANDRA T, GLAUSER MP, TÄUBER M, PITTET DIDIER

Quantifying Uncertainty: Physicians' Estimates of Infection in Critically Ill Neonates and Children
CLINICAL INFECTIOUS DISEASES
2004 vol. 38 pp. 1383-1390
FISCHER JE, HARBARTH STEPHAN, AGTHE AG, BENN A, RINGER SA, GOLDMANN DA, FANCONI S

G-CSF and Il-8 for early diagnosis of sepsis in neotates and critically ill children - safety and cost effectiveness of a new laboratory prediction model: study protocol of a randomized controlled tri al [ISRCTN91123847]
CRITICAL CARE
2004 vol. 8 pp. 443-450
HORISBERGER T, HARBARTH STEPHAN, NADAL D, BAENZIGER O, FISCHER JE

Adrenal insufficiency: the link between low apolipoprotein A-I levels and poor outcome in the critically ill?
CRITICAL CARE MEDICINE
2004 vol. 32 pp. 1978-1979
CHENAUD CATHERINE, MERLANI PAOLO, ROUX-LOMBARD-LATUNE PASCALE, BURGER DANIELLE, HARBARTH STEPHAN, LUYASU SAMUEL, GRAF JEAN-DANIEL, DAYER JEAN-MICHEL, RICOU BARA

Low apolipoprotein A-I level at intensive care unit admission and systemic inflammatory response syndrome exacerbation
CRITICAL CARE MEDICINE
2004 vol. 32 pp. 632-637
CHENAUD C, MERLANI P, ROUX LOMBARD P, BURGER D, HARBARTH S, LUYASU S, GRAF JD, DAYER JM, RICOU B

Nursing resources: a major determinant of nosocomial infection ?
CURRENT OPINION IN INFECTIOUS DISEASES
2004 vol. 17 pp. 329-333
HUGONNET STEPHANE, HARBARTH STEPHAN, SAX HUGO, DUNCAN R, PITTET DIDIER

Antibiotic Selection Pressure and Resistance in Streptococcus pneumoniae and Streptococcus pyogenes
EMERGING INFECTIOUS DISEASES (PRINT)
2004 vol. 10 pp. 514-517
ALBRICH WC, MONNET DL, HARBARTH STEPHAN

Nosocomial bloodstream infection and clinical sepsis
EMERGING INFECTIOUS DISEASES (PRINT)
2004 vol. 10 pp. 76-81
HUGONNET STEPHANE, SAX HUGO, EGGIMANN PHILIPPE, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

An outbreak of Pseudomonas Aeruginosa Pneumonia and Bloodstream Infection Associated With Intermittent Otitis Externa in a Healthcar Worker
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. 25 pp. 1083-1089
ZAWACKI A, O'ROURKE E, POTTER-BYNOE G, MACONE A, HARBARTH STEPHAN, GOLDMANN D

COST IMPLICATIONS OF SUCCESSFUL HAND HYGIENE PROMOTION
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. 25 pp. 264-266
PITTET DIDIER, SAX HUGO, HUGONNET STEPHANE, HARBARTH STEPHAN

Dynamics of bacterial hand contamination during routine neonatal care
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. 25 pp. 192-197
PESSOA DA SILVA CARMEN, DHARAN SASI, HUGONNET STEPHANE, TOUVENEAU S, POSFAY-BARBE KLARA, PFISTER RICCARDO, PITTET DIDIER

Impact of ventilator -associated pneumonia on resource utilization and patient outcome
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY : THE OFFICIAL JOURNAL OF THE SOCIETY OF HOSPITAL EPIDEMIOLOGISTS OF AMERICA
2004 vol. pp. 1090-1096
HUGONNET STEPHANE, EGGIMANN PHILIPPE, BORST FRANCOIS, PATRICE MARICOT, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Reply to letter by Tulleken et al.
INTENSIVE CARE MEDICINE
2004 vol. 30 pp. 998-999
EGGIMANN PHILIPPE, HUGONNET STEPHANE, SAX HUGO, CHEVROLET JEAN-CLAUDE, PITTET DIDIER

Semmelweis' legacy: insights from an international survey among 265,000 students in 32 countries
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
2004 vol. 207 pp. 1-5
HARBARTH STEPHAN, ALBRICH W, PITTET DIDIER

A novel multiplex real-time PCR assay for rapid typing of major staphylococcal cassette chromosome mec elements
JOURNAL OF CLINICAL MICROBIOLOGY
2004 vol. 42 pp. 3309-3312
FRANCOIS PATRICE, RENZI GESUELE, PITTET DIDIER, BENTO MANUELA, LEW DANIEL, HARBARTH STEPHAN, VAUDAUX PIERRE, SCHRENZEL JACQUES

The Lowbury lecture: behaviour in infection control
JOURNAL OF HOSPITAL INFECTION
2004 vol. 58 pp. 1-13
PITTET DIDIER

Is anti-tumor necrosis factor therapy associated with increased mortality in patients with severe sepsis caused by pneumonia?
JOURNAL OF INFECTIOUS DISEASES
2004 vol. pp. 1743-1743
HARBARTH STEPHAN, GARBINO JORGE, PITTET DIDIER, PUGIN JEROME

Comparative analysis and validation of different assays for glycopeptide susceptibility among methicillin-resistant staphylococcus aureus strains
JOURNAL OF MICROBIOLOGICAL METHODS
2004 vol. 57 pp. 231-239
BERNARD L, VAUDAUX P, ROHNER P, HUGGLER E, ARMANET M, PITTET D, LEW DP, SCHRENZEL J

Clean hands reduce the burden of disease
LANCET
2004 vol. 366 pp. 185-187
PITTET DIDIER

Catheter-related infections
MICROBES AND INFECTION : A JOURNAL ON INFECTIOUS AGENTS AND HOST DEFENSES
2004 vol. 6 pp. 1033-1042
EGGIMANN PHILIPPE, SAX HUGO, PITTET DIDIER

Enjeux, stratégie de traitement et évolution clinique des bactérémies à SARM
PRESSE MEDICALE (DES 1983)
2004 vol. 12 pp. 10-17
PITTET DIDIER

Control of multiply resistant cocci: Do international comparisons help?
THE LANCET INFECTIOUS DISEASES
2001 vol. 1 pp. 251-261
HARBARTH STEPHAN, ALBRICH W.C, GOLDMANN D.A, HUBNER J

Risk factors for persistent carriage of methicillin resistant Staphylococcus aureus
CLINICAL INFECTIOUS DISEASES.
2000 vol. 31(6) pp. 1380-1385
HARBARTH S, LIASSINE N, DHARAN S, HERRAULT P, AUCKENTHALER R, PITTET D

Effect of delayed infection control measures on a hospital outbreak of MRSA
JOURNAL OF HOSPITAL INFECTION
2000 vol. 46 pp. 43-49
HARBARTH STEPHAN, MARTIN PIERRE-YVES, ROHNER PETER, HENRY N, AUCKENTHALER R, PITTET DIDIER

Effectiveness of a hospital wide programme to improve compliance with hand hygiene Infection Control Programme
LANCET
2000 vol. 356 pp. 1307-1312
PITTET D, HUGONNET S, HARBARTH S, MOUROUGA P, SAUVAN V, TOUVENEAU S, PERNEGGER TV

Impact of methicillin resistance on the outcome of patients with bacteremia caused by Staphylococcus aureus
ARCHIVES OF INTERNAL MEDICINE
1998 vol. 158 pp. 182-189
HARBARTH STEPHAN, RUTSCHMANN OLIVIER, SUDRE PHILIPPE, PITTET DIDIER


Domaines de recherche

INFECTION NOSOCOMIALE
EPIDEMIOLOGIE
FACTEUR DE RISQUE
HYGIENE HOSPITALIERE
QUALITE DES SOINS