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Group's publications

Synovial tissues concentrate secreted APRIL.
ARTHRITIS RESEARCH & THERAPY
2009 vol. 11(5) pp. 144-144
GABAY C, KRENN V, BOSSHARD C, SEEMAYER CA, CHIZZOLINI C, HUARD B

Tumors that look for their springtime in APRIL.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
2009 vol. 72(2) pp. 91-97
ROOSNEK E, BURJANADZE M, DIETRICH PY, MATTHES T, PASSWEG J, HUARD B

In situ detection of APRIL-rich niches for plasma-cell survival and their contribution to B-cell lymphoma development.
HISTOLOGY AND HISTOPATHOLOGY
2009 vol. 24(8) pp. 1061-1066
BURJANADZE M, MATTHES T, MCKEE T, PASSWEG J, HUARD B

Comment on "Dendritic cells and monocyte/macrophages that create the IL-6/APRIL-rich lymph node microenvironment where plasmablasts mature".
JOURNAL OF IMMUNOLOGY
2009 vol. 182(9) pp. 5159-5159
BELNOUE E, MATTHES T, SIEGRIST CA, HUARD B

Lymph node tumor metastases: more susceptible than primary tumors to CD8(+) T-cell immune destruction
TRENDS IN IMMUNOLOGY
2009 vol. 30(12) pp. 569-573
CONTASSOT E, PREYNAT-SEAUVE O, FRENCH L, HUARD B

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.
BLOOD
2008 vol. 111(5) pp. 2755-2764
BELNOUE E, PIHLGREN BOSCH MARIA, MC GAHA T, TOUGNE C, ROCHAT AF, BOSSEN C, SCHNEIDER P, HUARD B, LAMBERT PH, SIEGRIST CA

Heparan sulfate proteoglycans, Fc receptors, and DC suppression.
BLOOD
2008 vol. 112(3) pp. 915-916
ROOSNEK E, SCHNEIDER P, HUARD B

Human NK cells can control CMV infection in the absence of T cells.
BLOOD
2008 vol. 112(3) pp. 914-915
KUIJPERS TW, BAARS PA, DANTIN C, VAN DEN BURG M, VAN LIER RA, ROOSNEK E

Quality of life and social integration after allogeneic hematopoietic SCT.
BONE MARROW TRANSPLANTATION
2008 vol. 42(12) pp. 819-827
BIERI S, ROOSNEK E, HELG C, VERHOLEN F, ROBERT D, CHAPUIS B, PASSWEG JAKOB, MIRALBELL R, CHALANDON Y

Direct presentation of a melanocyte-associated antigen in peripheral lymph nodes induces cytotoxic CD8+ T cells.
CANCER RESEARCH
2008 vol. 68(20) pp. 8410-8418
SCHULER P, CONTASSOT E, IRLA M, HUGUES S, PREYNAT-SEAUVE O, BEERMANN F, DONDA A, FRENCH LE, HUARD B

Role of the tumour necrosis family ligand APRIL in solid tumour development: Retrospective studies in bladder, ovarian and head and neck carcinomas.
EUROPEAN JOURNAL OF CANCER
2008 vol. 44(15) pp. 2097-2100
MHAWECH-FAUCEGLIA P, ALLAL ABDELKARIM, ODUNSI K, ANDREWS C, HERRMANN FR, HUARD B

Role of the tumor necrosis factor ligand APRIL in Hodgkin's lymphoma: a retrospective study including 107 cases.
EXPERIMENTAL HEMATOLOGY
2008 vol. 36(5) pp. 533-534
WENT P, TZANKOV A, SCHWALLER J, PASSWEG JAKOB, ROOSNEK E, HUARD B

APRIL secreted by neutrophils binds to heparan sulfate proteoglycans to create plasma cell niches in human mucosa.
JOURNAL OF CLINICAL INVESTIGATION
2008 vol. 118(8) pp. 2887-2895
HUARD B AND AL

Human cytomegalovirus infection induces a rapid and sustained change in the expression of NK cell receptors on CD8+ T cells.
JOURNAL OF IMMUNOLOGY
2008 vol. 180(7) pp. 4550-4560
VAN STIJN A, ROWSHANI AT, YONG SL, BAAS F, ROOSNEK E, TEN BERGE IJ, VAN LIER RA

Reconstitution of the immune system after hematopoietic stem cell transplantation in humans.
SEMINARS IN IMMUNOPATHOLOGY
2008 vol. 30(4) pp. 425-437
STOREK J, GEDDES M, KHAN F, HUARD B, HELG C, CHALANDON Y, PASSWEG JAKOB, ROOSNEK E

Presence of CD4+CD8+ double-positive T cells with very high interleukin-4 production potential in lesional skin of patients with systemic sclerosis
ARTHRITIS AND RHEUMATISM --
2007 vol. 56(10) pp. 3456-3467
PAREL YANN, AURRAND-LIONS MICHEL, SCHEJA AGNETA, DAYER JEAN-MICHEL, ROOSNEK EDDY, CHIZZOLINI CARLO

Neutrophil-derived APRIL concentrated in tumor lesions by proteoglycans correlates with human B-cell lymphoma aggressiveness
BLOOD
2007 vol. 109(1) pp. 331-338
SCHWALLER J, SCHNEIDER P, MHAWECH-FAUCEGLIA P, MCKEE T, MYIT S, MATTHES T, TSCHOPP J, DONZE O, LE GAL FA, HUARD B

Extralymphatic tumors prepare draining lymph nodes to invasion via a T-cell cross-tolerance process
CANCER RESEARCH
2007 vol. 67 pp. 5009-5016
PREYNAT-SEAUVE O, CONTASSOT E, SCHULER P, PIGUET V, FRENCH LE, HUARD B

A new subset of human naive CD8(+) T cells defined by low expression of IL-7R alpha
JOURNAL OF IMMUNOLOGY
2007 vol. 179 pp. 221-228
ALVES NL, VAN LEEUWEN EM, REMMERSWAAL EBM, VRISEKOOP N, TESSELAAR K, ROOSNEK E, TEN BERGE IJM, VAN LIER RAW

Paracrine promotion of tumor development by the TNF ligand APRIL in Hodgkin's Disease
LEUKEMIA
2007 vol. 21(6) pp. 1324-1327
SCHWALLER J, WENT P, MATTHES T, DIRNHOFER S, DONZE O, MHAWECH-FAUCEGLIA P, MYIT S, HUARD B

Melanoma-infiltrating dendritic cells induce protective antitumor responses mediated by T cells
MELANOMA RESEARCH
2007 vol. 17 pp. 169-176
PREYNAT-SEAUVE O, CONTASSOT E, SCHULER P, FRENCH LE, HUARD B

HLA and KIR polymorphisms affect NK-cell anti-tumor activity
TRENDS IN IMMUNOLOGY
2007 vol. 28 pp. 437-441
PASSWEG JR, HUARD B, TIERCY JM, ROOSNEK E

Can only partial T-cell depletion of the graft before hematopoietic stem cell transplantation mitigate graft-versus-host disease while preserving a graft-versus-leukemia reaction? A prospective phase II study
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
2006 vol. 12 pp. 102-110
CHALANDON Y, ROOSNEK E, MERMILLOD B, WAELCHLI L, HELG C, CHAPUIS B

Pretransplantation CMV-specific T cells protect recipients of T-cell-depleted grafts against CMV-related complications
BLOOD
2006 vol. 07(1) pp. 389-396
CHALANDON Y. ET AL.

Impact of high-resolution matching in allogeneic unrelated donor stem cell transplantation in Switzerland
BONE MARROW TRANSPLANTATION
2006 vol. 37 pp. 909-916
CHALANDON Y, TIERCY JM, SCHANZ U, GUNGOR T, SEGER R, HALTER J, HELG C, CHAPUIS B, GRATWOHL A, TICHELLI A, DE FAVERI GN, ROOSNEK E, PASSWEG J

Tumor-infiltrating dendritic cells are potent antigen-presenting cells able to activate T cells and mediate tumor rejection
JOURNAL OF IMMUNOLOGY
2006 vol. 176 pp. 61-67
PREYNAT-SEAUVE O, SCHULER P, CONTASSOT E, BEERMANN F, HUARD B, FRENCH LE

The source of APRIL up-regulation in human solid tumor lesions
JOURNAL OF LEUKOCYTE BIOLOGY
2006 vol. 80 pp. 697-704
MHAWECH-FAUCEGLIA P, KAYA G, SAUTER G, MCKEE T, DONZE O, SCHWALLER J, HUARD B

A CD40-CD95L fusion protein interferes with CD40L-induced prosurvival signaling and allows membrane CD40L-restricted activation of CD95.
JOURNAL OF MOLECULAR MEDICINE
2006 vol. 84(9) pp. 785-797
ASSOHOU-LUTY C, GERSPACH J, SIEGMUND D, MÜLLER N, HUARD B, TIEGS G, PFIZENMAIER K, WAJANT H

Transient hemophagocytosis with deficient cellular cytotoxicity, monoclonal immunoglobulin M gammopathy, increased T-cell numbers, and hypomorphic NEMO mutation
PEDIATRICS
2006 vol. 117 pp. 1049-1056
SCHMID JMP, JUNGE SA, HOSSLE JP, SCHNEIDER EM, ROOSNEK E, SEGER RA, GUNGOR T

Association of TNFd and IL-10 polymorphisms with mortality in unrelated hematopoietic stem cell transplantation
TRANSPLANTATION
2006 vol. 81(9) pp. 1261-1267
BETTENS FLORENCE ET AL.

Impaired CD40L signaling is a cause of defective IL-12 and TNF-alpha production in Sézary syndrome: circumvention by hexameric soluble CD40L
BLOOD
2005 vol. 105(1) pp. 219-225
FRENCH LE, HUARD B, WYSOCKA M, SHANE R, CONTASSOT E, ARRIGHI JF, PIGUET V, CALDERARA S, ROOK AH

Identification of proteoglycans as the APRIL-specific binding partners
JOURNAL OF EXPERIMENTAL MEDICINE
2005 vol. 201 pp. 1375-1383
INGOLD K ET AL.

Immunité cellulaire: les leçons de la transplantation de moelle osseuse allogénique (TMO)
MEDECINE ET HYGIENE : JOURNAL SUISSE D'INFORMATIONS MEDICALES
2002 vol. 60 pp. 395-399
VILLARD J, CHAPUIS B, HELG C, ROOSNEK E

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Research's domains